Product Introduction

　　Although 6-FAM has been commonly used to develop various qPCR probes, its fluorescence has two limitations of use: a) it is highly pH dependent; b) Rapid photobleaching. FAM-xtra phosphamide was developed to address these two limitations, while the ease of operation of 6-FAM phosphamide was fully maintained. FAM-xtra phosphamide can be used exactly the same as 6-FAM phosphamide under the same operating conditions without any modification.

　　Oligonucleotides made from FAM-xtra phosphamide have considerable advantages over 6-FAM-labeled nucleotides: a) identical spectra; b) the fluorescence of FAM-xtra oligonucleotide was brighter; c)FAM-xtra oligonucleotide has higher photostability; d) The fluorescence of FAM-XTRA-labeled oligonucleotides is much less sensitive to pH. Under physiological conditions, the fluorescence of FAM-XTRA-labeled oligonucleotides is essentially PH-independent, which makes FAM-XTRA-labeled oligonucleotides more reliable.

　　Excitation wavelength (nm) : 493

　　Emission wavelength (nm) : 517

　　Changsha HanchBio has completed the process development of the product, which can easily realize the synthesis of the product at the level of 100 grams, and meet the customers' purchasing needs in large quantities. At present, the product has been provided to a large number of domestic IVD enterprises, the difference between batches is small, the product quality is stable and reliable.