Product Introduction

　　Acridine esters (NSP-SA-NHS) and related compounds have proven to be highly advantageous chemiluminescence markers, with stability, activity, and sensitivity exceeding those of radioisotopes. Acridine ester can react with any protein that contains an amino group. Under alkaline conditions, the NHS will leave and the acridine ester will bind to the protein with a stable amide bond to form an acridine compound. After completion of the reaction, excess acridine salts were removed through a desalination column. In the presence of basic hydrogen peroxide, the acridine-labeled protein fluoresces itself without enzymatic catalysis. When the excitation reagent is added, the system immediately releases photons, which can be detected with a standard 430nm photometer. The process is so short (the entire process takes place in less than two seconds) that an internal photometer and photon detector must be added to the trigger scheme. Proteins, peptides, antibodies, nucleic acids can all be labeled with acridine. The labeled compounds emit light rapidly under the excitation of alkaline hydrogen peroxide and can be detected by collecting photons.

　　Main applications: chemiluminescence, immunoassay, receptor assay, nucleic acid and polypeptide detection, etc.

　　Acridine ester (NSP-NSA-NSH) was prepared and purified by HPLC and the purity was higher than that of existing products on the market. The product has been provided to many domestic chemiluminescence IVD enterprises, product quality has been verified, customer feedback is stable and reliable!